Challenges of teacher recruitment and retention in rural areas continue to plague our nation. South Carolina is no exception. Identifying promising practices to meet these challenges is critical as 24% (12 million) of our nation’s students and 40% of our South Carolina students are educated in rural schools. In this paper, we discuss challenges facing rural schools associated with teacher recruitment and retention, highlight promising practices identified through a comprehensive literature review, and conclude with recommendations for meeting these challenges. While we include the national perspective, we also specifically examine these areas of focus from a South Carolina centric lens.